Is it better to sleep on the plane?

Only if it is nighttime at your destination. If it is daytime at your destination, force yourself to stay awake until at least 8:00 PM local time.

Should I use sleeping pills?

Consult a doctor first. Many frequent travelers use low-dose melatonin, but prescription sleep aids can leave you with a 'hangover' effect that makes business meetings difficult.

Minimizing Jet Lag During Business Travel

Adjust your internal clock by shifting your sleep schedule by one hour per day for three days before departure. Once you land, strictly follow the local time for meals and sleep to force your body to sync with the new time zone.

Pre-departure adjustment. Three days before you fly, start moving your bedtime and wake-up time by one hour toward your destination's time zone. If flying East, go to bed earlier; if flying West, go to bed later.
Optimize your flight. Set your watch to the destination time the moment you board the plane. Avoid alcohol and heavy caffeine, as both disrupt the sleep cycles you need to anchor your body to the new time zone.
Use light as a tool. Seek bright, natural sunlight during the morning hours of your destination to signal wakefulness to your brain. If you arrive in the evening, use sunglasses or dim lights to encourage melatonin production.
Strategic napping. Never nap for longer than 20 minutes during the day. If you must sleep, do it before 3:00 PM local time so you don't compromise your ability to fall asleep at a normal local bedtime.

Is it better to sleep on the plane?: Only if it is nighttime at your destination. If it is daytime at your destination, force yourself to stay awake until at least 8:00 PM local time.
Should I use sleeping pills?: Consult a doctor first. Many frequent travelers use low-dose melatonin, but prescription sleep aids can leave you with a 'hangover' effect that makes business meetings difficult.