How to plan your first backpacking route through South America

Start with the classic gringo trail hitting Peru, Bolivia, and either Chile or Argentina over 2-3 months. Book your first few nights in Lima or Buenos Aires, get a rough north-to-south or south-to-north route mapped out, and leave room to adjust based on weather and what other travelers recommend on the ground.

  1. Pick your entry and exit points. Most first-timers start in Lima, Peru or Buenos Aires, Argentina. Lima gives you immediate access to Machu Picchu and the classic northern route. Buenos Aires sets you up for Patagonia and working north. Book flights to one, out of the other — or same city if you're doing a loop.
  2. Map the backbone route first. Plan your major stops: Lima → Cusco → La Paz → either Santiago/Buenos Aires or reverse. This hits Peru, Bolivia, and Chile/Argentina. Add Ecuador (Quito, Galapagos) if starting north, or Brazil (Rio, Iguazu Falls) if you have extra time. Don't try to hit every country your first trip.
  3. Time it around weather and seasons. Dry season in Peru/Bolivia is May-September. Patagonia hiking season is December-March. If doing both, start north in April-May or start south in November-December. Avoid Bolivian salt flats in rainy season (December-March).
  4. Book your first 3-5 nights only. Reserve hostels in your arrival city and maybe Cusco if doing Machu Picchu early. Don't book everything — you'll meet people and change plans. Use Hostelworld for the main stops, local guesthouses for smaller towns.
  5. Plan around the must-dos. Machu Picchu requires advance booking (especially for hiking permits). Book 2-3 months ahead. Patagonia refugios fill up for December-February. Everything else can be booked 1-7 days ahead as you travel.
  6. Build in buffer time. Add 2-3 extra days between major destinations. Buses break down, weather delays flights, you'll want to stay longer places you love. Better to have time than be constantly rushing to catch up to an overpacked schedule.
How much Spanish do I need?
Basic Spanish helps enormously. Learn numbers, directions, food words, and "How much?" Most hostel staff speak some English, but outside tourist areas Spanish is essential. Download offline translation apps as backup.
Is it safe to travel alone?
Yes, especially on the main backpacker routes. Hostels are social, you'll meet other travelers constantly. Use common sense — don't flash valuables, trust your gut about people and situations, stay in well-reviewed hostels.
Should I book buses in advance?
Only for major routes during peak season (Cusco to La Paz, Buenos Aires to Mendoza). Most routes you can book 1-2 days ahead. Book same day for local buses. Night buses on popular routes fill up faster.
What about altitude sickness?
It's real and can hit anyone. Fly into Cusco (11,000 feet) slowly if possible. Stay hydrated, avoid alcohol first few days, consider altitude sickness meds. La Paz is even higher. Listen to your body.