Is it better to stay in La Paz or lower-altitude areas?

If you are very sensitive to altitude, consider staying in the neighborhood of Calacoto, which is about 300 meters lower than the city center.

How do I know if it's just altitude or something serious?

If you cannot catch your breath while resting, or if you have a persistent dry cough, go to a medical clinic immediately. This could indicate pulmonary edema.

How to Acclimatize to the Altitude in La Paz

To acclimatize to La Paz's 3,640-meter elevation, spend your first 48 hours resting and avoid strenuous physical activity. Stay hydrated, prioritize complex carbohydrates, and consult a doctor about taking acetazolamide before you arrive.

Pre-departure preparation. Schedule a visit with your doctor 4 weeks before your trip to discuss acetazolamide (Diamox). If cleared, start taking a half-dose 24 hours before your flight to prime your system.
The first 48-hour rule. Do not book trekking or city walking tours for your first two days. Sleep, drink water, and let your oxygen saturation levels stabilize as your body produces more red blood cells.
Eat for elevation. Focus on high-carb, low-fat meals. Digestion consumes significant oxygen, and heavy fats or proteins will leave you feeling winded and sluggish.
Hydrate aggressively. Drink 3 liters of water daily. The dry air in the Andes causes rapid fluid loss through respiration, which exacerbates altitude headaches.
Use local remedies. Drink coca leaf tea (mate de coca). It is served everywhere in La Paz and helps alleviate the mild symptoms of altitude sickness.

Is it better to stay in La Paz or lower-altitude areas?: If you are very sensitive to altitude, consider staying in the neighborhood of Calacoto, which is about 300 meters lower than the city center.
How do I know if it's just altitude or something serious?: If you cannot catch your breath while resting, or if you have a persistent dry cough, go to a medical clinic immediately. This could indicate pulmonary edema.