Is it safe to travel by bus at night?

Stick to reputable companies like Cruz del Sur or Flecha Bus. Avoid smaller, budget-only carriers for overnight segments to ensure driver quality and vehicle maintenance.

How do I handle altitude sickness?

Stay hydrated, avoid alcohol for the first 48 hours at high altitude, and consider carrying Acetazolamide (Diamox) if your doctor prescribes it.

Planning an Overland Route from Lima to Buenos Aires

Crossing from Lima to Buenos Aires requires at least 21 days to handle the high-altitude transit through the Andes and the vast distances across Bolivia and Northern Argentina. You will primarily use long-distance 'cama' (sleeper) buses to traverse the continent, stopping at major transit hubs to break up 15-20 hour travel stretches.

Map the primary route. The most logical route is Lima -> Cusco -> Lake Titicaca (Puno) -> La Paz -> Uyuni -> Salta -> Buenos Aires. This takes you through the heart of the Andes before descending into the Argentine pampas.
Acclimatize in Cusco. Do not rush from sea level in Lima to high-altitude La Paz. Spend at least 3-4 days in Cusco (3,400m) to adjust to the elevation before attempting the higher border crossings into Bolivia.
Book buses locally or via aggregator apps. Use platforms like Busbud or TicketsBolivia to check schedules, but always buy your tickets at the bus terminal 24 hours in advance to secure specific seat numbers and avoid middle-man fees.
Prepare for border bureaucracy. Carry your passport and at least three printed copies of your entry stamp and visa (if applicable). Some border crossings, especially between Bolivia and Argentina, require a physical 'Salida' stamp that you must actively seek out at the immigration office.

Is it safe to travel by bus at night?: Stick to reputable companies like Cruz del Sur or Flecha Bus. Avoid smaller, budget-only carriers for overnight segments to ensure driver quality and vehicle maintenance.
How do I handle altitude sickness?: Stay hydrated, avoid alcohol for the first 48 hours at high altitude, and consider carrying Acetazolamide (Diamox) if your doctor prescribes it.