How to plan an overland route from Lima to Buenos Aires

The overland route from Lima to Buenos Aires covers roughly 3,000 miles and takes 3-6 weeks depending on your pace. The main route goes through Peru, Bolivia, and Argentina, with optional detours through Chile. Plan for altitude changes, border crossings, and varying road conditions.

  1. Map your core route. The standard route: Lima → Huacachina → Arequipa → Puno → La Paz → Uyuni → Salta → Mendoza → Buenos Aires. This hits the major highlights while maintaining reasonable travel times between stops. Download offline maps for areas with poor internet coverage.
  2. Plan for altitude adjustment. You'll go from sea level to 12,000+ feet multiple times. Spend 2-3 days in Cusco or Arequipa before heading to higher altitudes in Bolivia. Stock up on coca leaves and altitude sickness medication. Avoid alcohol for the first 48 hours at high altitude.
  3. Research border crossings. Peru-Bolivia crossing at Kasani/Yunguyo is most common for overland travelers. Bolivia-Argentina at La Quiaca is straightforward but can be slow. Keep copies of all documents and have cash for exit taxes. Some borders close overnight.
  4. Book key transportation segments. Reserve Uyuni salt flats tours 2-3 days in advance. Book overnight buses for long stretches like La Paz to Uyuni (10 hours) and Salta to Mendoza (14 hours). Flying Lima to Arequipa saves 16 hours of bus time for $80-120.
  5. Plan for weather and seasons. April-September is dry season for most of the route. Avoid January-March for Uyuni (flooding) and December-February for northern Argentina (extreme heat). Pack layers for temperature swings from 30°F in Uyuni to 90°F in Salta.
  6. Prepare backup routes. Road closures and strikes are common. Alternative: fly Lima to Santiago, then overland through Chile to Argentina. Or skip Uyuni if weather is bad and go direct La Paz to Salta via Tarija. Build 3-5 buffer days into your timeline.
Is it safe to travel overland through Bolivia?
Yes, but use common sense. Stick to main tourist routes, don't travel at night, and avoid political demonstrations. The biggest risks are altitude sickness and poor road conditions, not crime.
Can I do this route by car?
Yes, but you'll need a carnet de passage for temporary vehicle import and good Spanish skills for paperwork. Most overland travelers use buses and tours rather than driving themselves.
How long do border crossings take?
Plan 2-4 hours for each border crossing. Peru-Bolivia can be slower due to tourist volume. Arrive early in the day and have all documents ready. Some crossings close for lunch.
What if I get sick at high altitude?
Descend immediately if you have severe symptoms. Lima and Buenos Aires both have good medical facilities. Travel insurance is essential - evacuation from remote areas is expensive.