How to Pack for Malaria Prevention in Africa

Pack prescription antimalarials (get them 2-4 weeks before travel), DEET repellent with 20-30% concentration, permethrin-treated clothing, and a bed net rated for tropical use. Your malaria prevention strategy requires both medication and physical barriers.

  1. Get prescription antimalarials from a travel clinic. Visit a travel medicine clinic 4-6 weeks before departure. Bring your exact itinerary including cities and rural areas. Common prescriptions are doxycycline ($15-30 for a month supply), atovaquone-proguanil ($180-220), or mefloquine ($25-40). Start taking as directed - some begin 1-2 days before travel, others 1-2 weeks before.
  2. Pack DEET-based insect repellent. Bring repellent with 20-30% DEET concentration. Higher percentages last longer but aren't more effective. Pack 2-3 bottles for trips over 2 weeks. Sawyer Products Picaridin or OFF! Deep Woods are reliable options. Avoid repellents with less than 20% DEET for malaria zones.
  3. Treat clothing with permethrin or buy pre-treated items. Treat 2-3 complete outfits with Sawyer Permethrin spray ($12-15 per bottle) or buy permethrin-treated clothing from ExOfficio or Craghoppers. Treatment lasts through 6-20 washes. Focus on long pants, long-sleeve shirts, and socks you'll wear during dawn and dusk when mosquitoes are most active.
  4. Pack a proper bed net. Bring a permethrin-treated mosquito net rated for tropical use. Cocoon or Sea to Summit nets ($25-40) pack small and set up easily. Even if your accommodation claims to have nets, bring your own - hotel nets are often torn or untreated. Pack repair tape for tears.
  5. Add backup physical protection. Pack a portable fan for your room - mosquitoes are weak fliers. Bring permethrin-treated clothing for sleeping (lightweight long pants and long sleeves). Pack extra repellent applications for evening activities and dawn safaris when mosquito activity peaks.
Can I buy antimalarials in Africa instead of packing them?
Not recommended. Counterfeit antimalarials are common in many African countries, and you want to start your prevention regimen before arrival. Quality and availability vary significantly.
Do I need malaria prevention for city travel in South Africa or Morocco?
Cape Town, Johannesburg, and most of Morocco have no malaria risk. However, northern KwaZulu-Natal, Mpumalanga, and Limpopo provinces in South Africa do require prevention. Check current CDC maps for your specific destinations.
How much DEET repellent should I pack for a 3-week trip?
Pack 3-4 bottles of repellent for 3 weeks. You'll apply 2-3 times daily in malaria zones. A 6-ounce bottle typically lasts 7-10 days with regular use.
Is permethrin treatment really necessary if I have repellent?
Yes. DEET repellent wears off and you forget to reapply. Permethrin-treated clothing provides constant protection and lasts through multiple washes. It's your backup layer of defense.