How to Deal with Altitude Sickness in Cusco

Arrive in Cusco 2-3 days before any major activities, stay hydrated with 3-4 liters of water daily, and rest on your first day. Take acetazolamide (Diamox) if prescribed by your doctor, avoid alcohol and heavy meals, and descend immediately if symptoms worsen.

  1. Start prevention before you arrive. Get acetazolamide (Diamox) prescribed by your doctor 1-2 weeks before travel. Take 125mg twice daily starting 1-2 days before arrival. Avoid alcohol 24 hours before flying to Cusco.
  2. Plan a gentle arrival day. Book accommodation in central Cusco (3,400m) rather than higher areas like Sacsayhuamán. Schedule nothing strenuous for your first 24 hours. Walk slowly and take frequent breaks.
  3. Hydrate aggressively but smartly. Drink 3-4 liters of water daily, but sip slowly throughout the day rather than chugging. Avoid excessive caffeine which can dehydrate you. Coca tea helps with mild symptoms.
  4. Eat light and sleep elevated. Choose easily digestible foods like soups and avoid heavy, fatty meals for the first 2 days. Sleep with your head elevated using extra pillows to help with breathing.
  5. Recognize warning signs. Mild symptoms include headache, nausea, fatigue, and dizziness. Severe symptoms requiring immediate descent include confusion, difficulty walking, severe headache, or fluid in lungs (crackling sound when breathing).
  6. Adjust your itinerary if needed. If you feel unwell, postpone high-altitude activities like Rainbow Mountain (5,200m) or Machu Picchu. Spend extra days acclimatizing in Cusco before attempting day trips above 4,000m.
How long does it take to acclimatize to Cusco's altitude?
Most people feel better after 2-3 days, but full acclimatization takes 1-2 weeks. You can do light activities after day 2 if feeling well.
Can I drink alcohol in Cusco while acclimatizing?
Avoid alcohol for the first 48 hours as it worsens dehydration and altitude symptoms. After that, limit intake to 1-2 drinks maximum.
Is it safe to go directly from Cusco to Machu Picchu?
Machu Picchu (2,400m) is actually lower than Cusco, so it's safe to visit. The train ride down can even help with altitude adjustment.
What if I can't get Diamox before my trip?
Pharmacies in Cusco sell acetazolamide (called Acetazolamida) without prescription for about $10-15. Buy it immediately upon arrival.
When should I see a doctor in Cusco?
See a doctor immediately if you have severe headaches, confusion, difficulty walking, or breathing problems. Clinica Paredes is the best private clinic in central Cusco.