How to Book Flights for Multi-Country South America Trips

Book an open-jaw ticket (fly into one city, out of another) or use a round-trip to a hub city like Lima or São Paulo with separate regional flights. Start booking 2-3 months ahead for better prices, and consider getting a South America Airpass if visiting 3+ countries.

  1. Map your route first. List the countries and cities you want to visit in logical order. South America is huge — flying between distant cities like Buenos Aires to Bogotá costs $300-500. Plan your route to minimize backtracking.
  2. Choose your flight strategy. Option 1: Open-jaw ticket (fly into Lima, out of Buenos Aires). Option 2: Round-trip to a hub city + regional flights. Option 3: South America Airpass if visiting 3+ countries in one airline alliance.
  3. Book your international flights first. Use Google Flights or Skyscanner to compare prices. Major hubs: Lima (Peru), São Paulo (Brazil), Buenos Aires (Argentina), Bogotá (Colombia). Book 2-3 months ahead for best prices.
  4. Research visa requirements before booking. Some countries require visas that take weeks to process. Brazil requires a visa for US citizens ($80, 2 weeks processing). Venezuela is extremely difficult to enter as a tourist.
  5. Book regional flights strategically. LATAM and Avianca dominate South American routes. Book these 4-6 weeks ahead. Budget airlines: Sky Airline (Chile), JetSmart (multiple countries), Flybondi (Argentina).
  6. Consider alternative transport. Buses are comfortable and cheap between neighboring countries. Buenos Aires to Santiago: 20-hour bus ($40) vs 2-hour flight ($150). Save flights for long distances like Brazil to Peru.
Is a South America Airpass worth it?
Only if you're visiting 3+ countries and flying 4+ times within South America. The pass costs $500-800 and requires you to book your international flight with the same airline alliance. Compare individual flight prices first.
Which airline has the best South America network?
LATAM has the most comprehensive network and flies to nearly every major South American city. Avianca is strong in northern countries (Colombia, Ecuador, Peru). Copa connects through Panama for US travelers.
Can I book flights once I'm there?
Yes, but expect to pay 20-50% more for last-minute bookings. Some routes only fly 2-3 times per week, so you might wait days for the next flight. Book major routes ahead, leave flexibility for shorter segments.
Do I need proof of onward travel?
Most South American countries require proof you're leaving. Print your flight confirmations or book a refundable ticket you can cancel later. Border officials will check this.
What about flying budget airlines?
Budget airlines like JetSmart and Sky Airline offer good value but charge for everything extra. Factor in baggage fees, seat selection, and food. They're reliable for short flights within regions.