How to Book Multi-City Flights for South American Travel

Book multi-city flights for South America using airline alliance routing tools or Google Flights' multi-city search. Plan your route logically (north to south or vice versa) and book 2-3 months ahead. Expect to pay 20-40% more than round-trip tickets, but you'll save on positioning flights between countries.

  1. Map your route logically. Plan either north-to-south (Colombia → Ecuador → Peru → Bolivia → Chile → Argentina) or south-to-north. Avoid backtracking. Popular circuits: Lima-Cusco-La Paz-Santiago-Buenos Aires or Bogotá-Quito-Lima-Santiago-Buenos Aires.
  2. Choose your booking method. Use Google Flights multi-city search for price comparison across airlines. For complex routing, try airline alliance tools: Star Alliance (United/Avianca/Copa), OneWorld (American/LATAM), or SkyTeam (Delta/Aeromexico). Travel agents specializing in RTW tickets can help with 5+ city itineraries.
  3. Start with major hubs. Begin or end in major South American hubs: Lima (LIM), Buenos Aires (EZE), Santiago (SCL), or São Paulo (GRU). These have better international connections and competitive pricing. Bogotá (BOG) and Quito (UIO) work well for northern routes.
  4. Check visa requirements for your route. Some routing requires transit visas. US citizens need visas for Brazil but not for airport transit under 24 hours. Plan your entry/exit points around visa requirements—Brazil visa covers multiple entries for 90 days.
  5. Book 60-90 days in advance. Multi-city fares have limited seats. Book 2-3 months ahead for best prices. Avoid booking during South American summer (December-February) and major holidays. Shoulder seasons (March-May, September-November) offer better availability.
  6. Consider open-jaw alternatives. Sometimes booking separate round-trip tickets to different countries costs less than multi-city. Compare: NYC-Lima + Buenos Aires-NYC separately vs. NYC-Lima-Buenos Aires-NYC multi-city. Factor in positioning flight costs.
Is it cheaper to book multi-city or separate flights?
Multi-city tickets cost 20-40% more than single-destination round-trips but often less than buying separate international flights to each country. Calculate the total cost including positioning flights—if you're hitting 4+ countries, multi-city usually wins.
Can I change dates on multi-city tickets?
Change policies vary by airline and fare class. Most multi-city tickets allow date changes for $200-300 per segment plus fare difference. Route changes (switching cities) are usually not permitted. Buy flexible fares if you need change options.
What if I miss a connection in my multi-city itinerary?
If flights are on the same ticket, the airline will rebook you at no charge. Allow minimum 2-hour connections for domestic flights, 3+ hours for international connections in South America. Consider overnight layovers in major hubs to reduce missed connection risk.
Should I book hotels before confirming my flight route?
Book flights first, then accommodation. Multi-city flight availability changes quickly, and you may need to adjust your ground route based on flight schedules and prices. Leave 1-2 flexible days between cities for travel delays.