Planning a Two-Week Backpacking Trip Through Bolivia

Focus your two weeks on the 'Gringo Trail' loop to manage the high altitude and massive distances. Start in Santa Cruz or La Paz, hit the Salt Flats, and prioritize high-altitude acclimation before pushing into the desert.

  1. Master the Altitude. Fly into Santa Cruz (400m) first instead of La Paz (3,600m). Spend 2 days there before heading to higher elevations to avoid severe altitude sickness.
  2. Use Overnight Buses for Distance. Bolivia is large and roads are slow. Book 'cama' (full-flat seat) buses for overnight journeys between Sucre, Potosi, and Uyuni to save on a night of accommodation and gain daylight hours.
  3. Book the Salt Flats Locally. Do not book your Uyuni Salt Flats tour online from home. You will pay double. Book it in person at a reputable agency in Uyuni or La Paz the day before you intend to depart.
  4. Carry Cash. Outside of La Paz and Santa Cruz, ATMs are unreliable. Withdraw 1,000–1,500 Bolivianos at a time in major cities to ensure you have enough for rural tours and food.
Is it safe to travel alone in Bolivia?
Yes, but stick to official bus companies and reputable tour operators. Avoid walking alone at night in major cities.
Do I need to speak Spanish?
Basic Spanish is extremely helpful, especially for negotiating transport. Download offline maps and a translator app.