How to Plan a Bolivia Trip Without Getting Altitude Sickness

Spend your first 48 hours at a lower elevation in Santa Cruz before flying into the high-altitude hubs like La Paz or Uyuni. Prioritize hydration, avoid alcohol for the first three days, and consult your doctor about acetazolamide (Diamox) before departure.

  1. Start low, go high. Avoid flying directly into La Paz (3,640m) if possible. Book a flight to Santa Cruz de la Sierra (400m) first to spend two days acclimating before heading to the Andes.
  2. Schedule a gradual ascent. If you must fly into La Paz, immediately take a bus or taxi down to the lower-lying 'Zona Sur' neighborhoods or head straight to Coroico (1,700m) for 24 hours to let your body adjust to the thinner air.
  3. Hydrate and supplement. Drink at least 3 liters of water daily. Use coca tea (mate de coca) which is readily available in hotels; it is a local mild stimulant that helps with minor symptoms like headaches.
  4. Pace your activity. Do not plan any strenuous trekking for the first 3 days of your trip. Keep your heart rate low and avoid heavy physical exertion until you no longer feel winded while walking up stairs.
Is it safe to use oxygen canisters sold in shops?
Yes. Most pharmacies and some kiosks in La Paz sell small oxygen canisters. They provide temporary relief if you feel lightheaded, but they are not a substitute for proper acclimation.
How long does it take to fully acclimate?
Most people feel "normal" within 72 hours, but your body continues to adjust for up to 10 days.