How to Avoid Altitude Sickness in Cusco and Machu Picchu

Arrive in Cusco 2-3 days early to acclimatize at 11,200 feet before visiting Machu Picchu. Take acetazolamide (Diamox) starting 1 day before arrival, drink 3-4 liters of water daily, and avoid alcohol for the first 48 hours.

  1. Start Diamox before you arrive. Take 125-250mg of acetazolamide twice daily, beginning 1 day before reaching Cusco. Continue for 2-3 days at altitude. Get a prescription from your doctor before traveling.
  2. Plan your arrival schedule. Fly into Cusco and stay put for 2-3 full days before any high-altitude activities. Do not go straight to Machu Picchu. Your body needs time to adjust to 11,200 feet.
  3. Hydrate aggressively. Drink 3-4 liters of water daily. Start before you arrive and continue throughout your stay. Your urine should be light yellow. Carry a 1-liter water bottle everywhere.
  4. Eat light and avoid alcohol. Skip heavy meals and alcohol for your first 48 hours. Eat small portions of carbohydrate-rich foods. One beer at altitude hits like three at sea level.
  5. Rest on arrival day. Check into your hotel and do nothing else. Take a nap. Walk slowly. If you feel dizzy or nauseous, lie down immediately. Don't push through symptoms.
  6. Recognize serious symptoms. Seek immediate medical attention for severe headache, vomiting, confusion, or difficulty breathing. These signal serious altitude sickness requiring descent and medical care.
Can I skip the acclimatization days and go straight to Machu Picchu?
Not recommended. Machu Picchu sits at 8,000 feet, but you'll pass through 11,200+ feet in Cusco. Many travelers who skip Cusco acclimatization get sick on the train or at the ruins.
What if I'm already taking medication for other conditions?
Tell your doctor about all medications before getting Diamox. It can interact with blood thinners, diabetes medications, and some blood pressure drugs.
Is coca tea actually helpful or just tourist marketing?
Coca tea provides mild relief for some people, but it's not a substitute for proper acclimatization. Think of it as a small comfort measure, not a cure. The caffeine can help with altitude headaches.
How quickly can altitude sickness symptoms appear?
Symptoms typically start 6-24 hours after arrival. Mild headache and fatigue are common first signs. Severe symptoms like vomiting or confusion require immediate medical attention and descent.