Do I need to speak Spanish?

In Santiago and major tourist hubs of Atacama, English is widely spoken, but learning basic phrases like 'cuánto cuesta' (how much) is polite and helpful.

Is it safe to drink the tap water?

In Santiago, it is safe. In San Pedro de Atacama, it is highly mineralized and often tastes poor; stick to bottled or filtered water.

How to Spend One Week in Chile: Santiago and the Atacama

To see the best of Chile in seven days, spend two days exploring Santiago's neighborhoods and four days in San Pedro de Atacama for the desert landscapes. Use a domestic flight to connect these two hubs to maximize your limited time.

Book your domestic flight early. Book a LATAM or Sky Airline flight from Santiago (SCL) to Calama (CJC). Do not attempt to drive; the distance is over 1,500 kilometers and takes 20+ hours.
Arrange airport transfers. Once in Calama, you need a pre-booked shuttle to reach your accommodation in San Pedro de Atacama. It is an 80-minute drive from the airport to the village.
Manage your altitude. San Pedro is at 2,400 meters. Drink at least 3 liters of water daily and avoid heavy alcohol consumption on your first two days to prevent altitude sickness.
Book tours in advance. Popular excursions like the Tatio Geysers fill up. Book through a local operator in San Pedro at least 48 hours before you plan to go.

Do I need to speak Spanish?: In Santiago and major tourist hubs of Atacama, English is widely spoken, but learning basic phrases like 'cuánto cuesta' (how much) is polite and helpful.
Is it safe to drink the tap water?: In Santiago, it is safe. In San Pedro de Atacama, it is highly mineralized and often tastes poor; stick to bottled or filtered water.